Abstract:

Primary angle closure glaucoma（PACG）is featured with elevated intraocular pressure due to blocking outflow of aqueous humor by synechia or appositional angle closure. Lens factors, such as lens thickness, lens position and relative lens position, lens vault, lens thickness to axial length factor and lens curvature play a very important role in the pathogenesis of PACG. But the static anatomy factors alone are not enough to explain the specificity of PACG. The dynamic changes of lens  mainly present as lens position and lens thickness change, which is decided by the zonule. The function of the lens zonule may be associated with the occurrence of the angle closure.   (Int Rev Ophthalmol,  2015,  39:     372-375)